Chromatography A superior formula

Chromatography A superior formula "Everything flows, everything changes." Heraclides "It is not difficult to understand, it's difficult to know." Skovoroda The theory of gas chromatography, by Van Deemter equation (1), shows that for every chromatographic separation, there is an optimum flow above and below the column , efficiency is reduced. In practice, the linear velocity of the sample area by the carrier, is in constant evolution and increases as it approaches the exit, which results in a non-effective use of part of the column. In this case the equation (1) characterizes the optimal separation process in this section of the chromatographic column through which the sample is based on an optional speed.In of equation (1) values are constant and the speed of the movement area sample, the constant changes in time. Therefore, the equation (1) the following form: (2) Where is the speed of the sample distance from the column and the changes - increases - in the current direction. This shows that HETP is not always optimal in all areas of the chromatographic column. Let the length of the chromatographic column, the pressure input of column and the pressure to 'exit of the column, the distance from a point on the chromatographic column from its bay. It 'obvious that the point on the column can be determined by the flow correlationThe at any point on the chromatographic column is at this point, as the input and output pressure of the column. But the pressure at any point of the column depends on the pressure input and output pressure of the chromatographic column and on the distance from the column input. Therefore, the rate of flow at any point of the column in case of permanent physical parameters of the chromatographic column can be considered as a function of pressure and, at this point, at the ends, and the distance from that point of the column is, therefore, l 'whole column chromatography is characterized by a multiple of equations (3). If input and output of the column, the pressure is kept constant, each section of the chromatographic column through which the sample moves to the area, is characterized by its equation of more (3). However, the linear velocity of the sample zone moving with the carrier gas can be kept constant with the planning of the pressure gradient along the column, over time, the realization of the function of the press - Location - the time constant the pressure difference Δ p at the ends of the chromatographic column during the entire cycle of analysis (Russia Patent "AS Hayrapetyan Chromatograph). The sample through the chromatographic column in time where the length of the chromatographic column and the velocity of the sample zone.The optimum pressure on the inlet and outlet of the chromatographic column in which a change at the same time, bywhere - injection, and - elution time . We mark the sections of the chromatographic column traveled from the sample with a velocity of carrier gas to the corresponding moments of time that - the beginning of the chromatographic column, and - at the end of the chromatographic column. Let the pressure of the moment of entry and exit of the column chromatography on correspondinglyThen are moments of time for the relevant sections of the chromatographic column, the pressure can be found working well thatas ASIN this case а build a matrix of pressure as follows: left in which each line is the column for printing pointsat a pressure inlet and outlet of the column at a time, while each column corresponds to the pressure on a point at timeThus moments of the matrix is as follows formThe first column of the matrix corresponds pressure input of column, the last in the shop. They are chosen so that the column in which the sample for a certain period of time, there will always be a constant pressure, the optimum volume. The first column corresponds to the time of introduction of the sample, and the last for the elution of the components separated by the column. Each element of the matrix corresponds to a specific flow rate at a given time. For each element of the matrix, there is a certain scale and its equation followingly be more (3). The matrix of elements, the passage of the sample with an optimum speed through the corresponding points in the column at certain moments of time are in yellow. To this can be writtenThe carrier gas pressure is programmed in such a way that ensures a constant optimum linear velocity of an imaginary point - the area of the sample, which travels with the carrier gas input from the output of the chromatographic column in time where Δ p constant at the ends during the entire cycle of analysis. The calculation model (of Hayrapetyan - Aghababyan) of the chromatographic analysis based on the Van Deemter equation describes in detail the aforementioned technological process of analysis and organization of various equation (3) the optimal conditions of analysis and guidance for achieving maximum efficiency of the column (Hayrapetyan impact). In other words, the pressure in the entry and exit of the chromatographic column is programmed so that the carrier gas flow rate in the column is the best in each section, for the necessary moments of time. The separation of the sample is limited by the number of equations (3), and all the equation (4) and therefore the maximum efficiency of the chromatographic column is reached (Hayrapetyan impact). PS CHROMABAROGRAPHY - a new conveniences ormula F: speed, capacity management, durability and maximum efficiency of the chromatography column.AFORMULA their superiority. The author Aram HAYRAPETYAN47 / 6 Vardanants Street, Vanadzor 377201, Republic of Armenia, Tel: (374) 512 0115 E-mail: invent@freenet.amWeb-site publications and articles: 57 books published, including 21 for individual creatorship certificates of USSR and Russia, Germany, Czechoslovakia and Bulgaria. Personal Data: Bo May 17, 1945, married, two children. Daughter bo 1972, married. Son, bo in 1977.